Managing sickle cell pain crises in children
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This study looks at how children with sickle cell disease experience and manage pain crises, known as vaso-occlusive crises. The goal is to better understand these events to improve care for children living with this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 1 and 18 years old.
- You must have a confirmed diagnosis of sickle cell disease (a blood test called hemoglobin electrophoresis or HPLC proves this).
- You must have had at least one hospital visit or stay for a sickle cell pain crisis.
- You cannot have another blood disorder like thalassemia.
- You cannot have other long-term health issues that might make pain confusing to study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether numbing a specific area (regional anesthesia) can reduce inflammation and pain during a sickle cell pain crisis. It may offer a new way to manage severe pain without strong medications.
This trial tests if an intravenous medication called L-citrulline can help treat pain crises in children and young adults with sickle cell disease. Participants receive either the study drug or a placebo while in the hospital for a severe pain episode.
This study looks at what causes pain in people with sickle cell disease. They hope to learn more about pain patterns to better help patients manage it.
This study tests if using a bedside ultrasound (a quick, painless scan) of the chest and lungs can help doctors better understand and manage pain crises in people with sickle cell disease. If you are in the hospital for a severe pain crisis, you may be able to join.
This trial tests whether a virtual reality (VR) experience can help reduce pain during a sickle cell “vaso-occlusive crisis,” which is an episode of sudden, severe pain. It’s offered alongside the care team’s usual pain management to see if VR makes pain feel better.
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
Hear when a new Sickle Cell Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.