Genetic study for early-onset or familial MPN
Part of Blood & lymphatic clinical trials.
This study explores whether certain inherited gene changes make people more likely to develop myeloproliferative neoplasms (MPNs). It is looking at patients who were diagnosed at a young age or have a family history of blood cancers, to better understand the genetic causes of these conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of blood cancer called a myeloproliferative neoplasm (MPN). This includes Polycythemia Vera, Essential Thrombocythemia, or Primary Myelofibrosis.
- You have already had a test to identify the main gene change (driver mutation) that caused your MPN.
- Either you were diagnosed with MPN before turning 27 years old, OR you have at least one close relative (first or second degree) with a blood cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses advanced DNA testing to look for inherited gene changes in people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). It may help explain whether your illness could be part of a family-linked risk syndrome, which can guide treatment and family planning.
This study looks at young people (children, teens, and adults under 30) who have a type of blood cancer called myeloproliferative neoplasm (MPN). It aims to better understand the disease and its complications over time, with the goal of improving care.
This study looks for inherited gene changes in people with certain blood cancers (myeloproliferative neoplasms) who have a family history of similar blood cancers. It aims to understand how genes might be passed down. You may be able to join if you have the cancer and a family member also had a blood cancer.
This study looks at the genetic changes that happen when a myeloproliferative neoplasm (a blood cancer that grows slowly) turns into acute myeloid leukemia (a more aggressive leukemia). By studying your bone marrow samples, researchers hope to find new ways to target and treat this type of leukemia.
This study looks at how 'epigenetic age' (a measure of certain changes in your DNA) relates to the way blood cancers called myeloproliferative neoplasms (MPNs) develop and progress. It may help doctors better understand and predict the course of these diseases.
This study tracks children and teens with certain rare blood cancers called myeloproliferative neoplasms (MPNs). By collecting information from many patients, doctors hope to better understand these conditions and improve care for young people.
Hear when a new Myeloproliferative Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.