Clin2
NCT07204392Possibly a fitRecruiting

Genetic study for early-onset or familial MPN

Myeloproliferative DiseaseGermline Mutation

Part of Blood & lymphatic clinical trials.

This study explores whether certain inherited gene changes make people more likely to develop myeloproliferative neoplasms (MPNs). It is looking at patients who were diagnosed at a young age or have a family history of blood cancers, to better understand the genetic causes of these conditions.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
313 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You have a type of blood cancer called a myeloproliferative neoplasm (MPN). This includes Polycythemia Vera, Essential Thrombocythemia, or Primary Myelofibrosis.
  • You have already had a test to identify the main gene change (driver mutation) that caused your MPN.
  • Either you were diagnosed with MPN before turning 27 years old, OR you have at least one close relative (first or second degree) with a blood cancer.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03058588Recruiting
Genetic testing study for inherited AML or MDS risk

This study uses advanced DNA testing to look for inherited gene changes in people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). It may help explain whether your illness could be part of a family-linked risk syndrome, which can guide treatment and family planning.

Brescia
NCT06923670Not yet recruiting
Inherited gene changes in blood cancers with family history

This study looks for inherited gene changes in people with myeloproliferative neoplasms (MPNs) who have a family history of similar blood disorders. If you qualify, it may help explain why some families have higher risk and could guide future screening.

NCT06715267Recruiting
MPN in youth: studying disease features and complications

This study looks at young people (children, teens, and adults under 30) who have a type of blood cancer called myeloproliferative neoplasm (MPN). It aims to better understand the disease and its complications over time, with the goal of improving care.

Brest
NCT06022341Not yet recruiting
Genetic study to find new treatments for leukemia after MPN

This study is looking at the genetic changes that happen when a myeloproliferative neoplasm (a type of blood cancer) turns into acute myeloid leukemia. It aims to find new treatments that target these specific changes.

NCT06022328Recruiting
Epigenetic age and prognosis in blood cancers

This study looks at how 'epigenetic age' (a measure of certain changes in your DNA) relates to the way blood cancers called myeloproliferative neoplasms (MPNs) develop and progress. It may help doctors better understand and predict the course of these diseases.

Bordeaux
NCT07832513Not yet recruiting
Pregnancy and myeloproliferative neoplasms study

This study looks at how pregnancy affects people with myeloproliferative neoplasms (MPNs), which are blood disorders that cause the body to make too many blood cells. It aims to learn more about outcomes for mothers and babies, and how to manage these conditions during pregnancy. You can join if you are pregnant and have an MPN.

Hear when a new Myeloproliferative Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.