Expanded access to eye drops for chronic eye graft-versus-host disease
Part of Eyes & vision, Immune system & allergy clinical trials.
This trial provides access to an investigational eye drop solution for people with chronic dry eye caused by graft-versus-host disease (GVHD) after a stem cell or bone marrow transplant. The goal is to see if the drops can help relieve eye discomfort and improve vision-related quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have chronic eye GVHD with at least mild dryness (Oxford grade 1 or higher) and a certain level of symptoms (OSDI score of 22 or more).
- You must be in generally stable health and able to attend study visits.
- You cannot have certain autoimmune diseases like rheumatoid arthritis, lupus, or scleroderma (though exceptions may be possible).
- You cannot have had eye surgery or laser treatment in the last 3 months, and you must agree to avoid all vaccinations during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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