Vancomycin to prevent C. diff infection in ICU patients
Treatments studied
Part of Infections clinical trials.
This trial tests whether giving vancomycin through a tube into the stomach can prevent a serious gut infection called C. diff in people who are very sick in the ICU and taking antibiotics. If you qualify, you might receive this medicine to lower your risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been in the hospital for at least 3 days and are taking IV or oral antibiotics for at least 3 days.
- You have at least 2 of these risk factors: age 65 or older, live in a nursing home, take acid reflux medicine, have inflammatory bowel disease, have a weak immune system (like from HIV, organ transplant, or long-term steroids), have kidney failure needing dialysis, have diabetes, need strong blood pressure medicine (norepinephrine), or were in the hospital in the last 30 days and got antibiotics then.
- You are not pregnant or breastfeeding.
- You are not currently in jail or prison.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether taking vancomycin by mouth can prevent another C. diff infection when you need to take other antibiotics. It’s for patients who recently had C. diff and are about to start a new antibiotic course.
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