Engineered immune cells for adults with liver and other solid tumors
Part of Cancer, Digestive system clinical trials.
This trial tests a new type of immune cell (CAR T cell) that targets a protein called GPC3 found on certain solid tumors. It aims to see if these cells are safe and can help adults with liver cancer or other GPC3-positive tumors that have not responded to standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a solid tumor that makes the GPC3 protein (tested by your doctor).
- You are able to take care of yourself (Karnofsky score at least 60%).
- Your doctor expects you to live more than 16 weeks.
- If you have liver cancer, it must be at a specific stage (A, B, or C) and your liver function must be well enough (Child-Pugh score less than 7).
- Your tumor has come back or not responded to at least one standard treatment and one salvage therapy.
- You have recovered from any side effects of prior cancer treatments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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