Valproate for persistent lazy eye in children and teens
Treatments studied
Part of Brain & nervous system, Eyes & vision clinical trials.
This trial tests if the medication valproate (a seizure drug) can improve vision in children and teens aged 8-17 who still have a lazy eye (amblyopia) even after wearing glasses or patching. It may help if your child's vision has stopped getting better with standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must be between 8 and 17 years old.
- They have a lazy eye caused by eyes turning in/out (strabismus) or a big difference in prescription between eyes (anisometropia).
- The weaker eye sees between 20/40 and 20/400, and the stronger eye sees at least 20/25.
- Their vision has not improved with at least 8 weeks of patching or glasses alone.
- Your child cannot have certain health issues like liver, kidney, or metabolic problems, or be on medications that interact with valproate.
- Girls who have started their period must use effective birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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