Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have at least two of these four conditions: a larger waist (men 35 inches or more, women 31 inches or more), high blood pressure (top number 120 or bottom number 80 or higher), high fasting blood sugar (100 mg/dL or higher), or high triglycerides (150 mg/dL or higher) or low "good" cholesterol (men under 40 mg/dL, women under 50 mg/dL).
- You have been diagnosed with mild or moderate sleep apnea (AHI score between 5 and 30).
- You do not have a major mental illness or severe anxiety/depression.
- You do not have other primary sleep disorders.
- Your BMI is 30 or less, and you have no serious chronic diseases like heart disease, diabetes, or kidney problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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