Flonoltinib for people with polycythemia vera
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This study tests a new pill, flonoltinib, for people with polycythemia vera whose blood counts are hard to control and who have not responded well to or couldn't tolerate current treatments. The goal is to see if the pill can lower the number of red blood cells and reduce symptoms, potentially reducing the need for frequent blood removal procedures.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have polycythemia vera and are resistant to or intolerant of standard treatments like hydroxyurea or interferon.
- You have needed blood removal (phlebotomy) recently, or your blood thickness (hematocrit) is still above 45% despite treatment.
- Your blood counts and liver/kidney function are within certain limits (will be checked with tests).
- You are able to care for yourself (ECOG score 0–2) and willing to sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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