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NCT07243366Possibly a fitNot yet recruiting

Immune cell therapy for severe myasthenia gravis

Refractory Myasthenia Gravis

Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.

This trial tests a new cell therapy using special immune cells (CAR-NK cells) that may help people whose myasthenia gravis has not improved with standard treatments. It aims to see if these cells can reduce muscle weakness and improve daily life.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
15 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You must be between 18 and 65 years old.
  • You must have a confirmed diagnosis of myasthenia gravis that has not improved with standard treatments.
  • A blood test must show you have AChR antibodies (a specific marker for this disease).
  • You must have significant weakness that affects daily activities (score of 6 or more on a standard scale).
  • You must have tried at least two standard treatments (like steroids or other immunosuppressants) and one biologic drug (such as efgartigimod, rituximab, or eculizumab) without enough improvement.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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