Combination therapy for advanced prostate cancer
Treatments studied
Part of Cancer, Hormones & metabolism, Kidney & urinary clinical trials.
This trial tests a new combination therapy for advanced prostate cancer that has stopped responding to standard hormone treatments. It combines a radioactive targeted treatment (Lutetium-177 DGUL) with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors and slow the cancer's growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a male aged 19 or older.
- You have prostate cancer that has spread to other parts of the body and is no longer curable by surgery or radiation.
- You have already been treated with a second-generation hormone therapy (like abiraterone or enzalutamide), but the cancer still grew.
- Your testosterone level is kept very low by ongoing hormone therapy (surgical removal of the testicles or medication).
- A special scan (PSMA PET) showed that your tumors have a high level of a specific target, which this treatment aims for.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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