Nicardipine through a lumbar drain for brain aneurysm bleeding
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving a blood pressure medication (nicardipine) directly into the spinal fluid through a lumbar drain can improve recovery after a brain aneurysm bleed. It is for patients who have had this type of bleed and are already having a lumbar drain placed for standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with a subarachnoid hemorrhage caused by a brain aneurysm (a burst blood vessel in the brain).
- Your condition is considered moderate or less severe, based on a neurological rating called the Hunt and Hess score of 3 or lower.
- Before this event, you were able to live independently without needing help from others for daily activities (modified Rankin scale 0 or 1).
- You have a lumbar drain in place or planned (a small tube in your lower back to drain spinal fluid), which is standard care.
- You or your legal representative can sign the consent form, and you are not pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether giving a medicine called nicardipine through a tube in the spine (intrathecal) helps prevent or treat blood vessel tightening that can happen after a brain aneurysm rupture. It is for people who have had a specific type of brain bleed and show signs of vessel spasm.
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