Safety of RG6496 in Huntington's disease
Part of Brain & nervous system, Genetic & congenital, Mental health clinical trials.
This is an early-phase study testing a new drug (RG6496) for people with Huntington's disease. The study will check the drug's safety and how the body processes it, and it requires two doses given about 6 months apart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have tested positive for the Huntington's gene with more than 39 CAG repeats.
- You must carry a specific SNP (a DNA marker) that the treatment targets.
- You should be able to walk without help, have some independence in daily tasks, and have mild to moderate movement symptoms.
- You must weigh at least 88 pounds (40 kg) and have a BMI between 18 and 32.
- You must not be pregnant, breastfeeding, or planning pregnancy during the study, and you cannot have had suicide thoughts or attempts in the past year.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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