Terlipressin vs somatostatin for cirrhosis bleeding with kidney dysfunction
Part of Digestive system, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial compares two medicines, terlipressin and somatostatin, to see which one better controls bleeding from enlarged veins in the esophagus or stomach in people with cirrhosis and kidney problems. The goal is to find a safer and more effective treatment for this serious condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 70 years old.
- You need a definite diagnosis of cirrhosis (scarring of the liver) and active bleeding from swollen veins in your esophagus or stomach (variceal bleeding).
- Your kidneys are not working well at the time of admission, but you do not have other kidney diseases (like chronic kidney disease or structural kidney damage).
- You have not had a liver transplant, TIPS (a procedure to reduce bleeding in the liver), or kidney replacement therapy (dialysis).
- You do not have serious heart, lung, or brain disease, acute liver failure, or cancer in the liver or kidneys.
- You are not pregnant or breastfeeding, and you have not been in another clinical study within the past 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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