Peripheral Helper T-cells in CVID

This trial looks at how breathing tests (spirometry) can help guide treatment decisions for people with CVID and airway disease who are already on immune globulin (IG) therapy. It may help your care team better monitor lung function using a specific breathing-test pattern.

This study looks at immune cells in tissues affected by chronic graft-versus-host disease (cGVHD), a common complication after a stem cell transplant. It aims to better understand the condition, which may lead to better treatments.

This study looks at the gut microbiome (the bacteria in your digestive system), diet, and quality of life in people with CVID, a condition that affects the immune system. It compares those who receive immunoglobulin therapy (antibody treatment) with those who do not, to see if there are differences that might help improve care.

This study collects blood (and sometimes related samples) to learn how genes and the immune system work in people with primary immunodeficiency (PID) or in family members who may not have it. The goal is to improve understanding of rare immune conditions and help guide future care.

This research study examines how the immune system malfunctions in patients with common variable immunodeficiency (CVID)—a condition where the body doesn't make enough antibodies to fight infections. Researchers want to understand the genetics and immune patterns to help develop better treatments. Family members may also be asked to participate to help identify genetic causes.

This study looks at how the immune system works in people who have abnormal immune function, often shown by unusual or repeated infections or long-lasting inflammation. It may involve tests using blood samples and storage of blood for future research.