Comparing two devices to close the left atrial appendage
Part of Heart & circulation clinical trials.
This trial compares two different devices (Amplatzer Amulet and LAmbre) used to close a small pouch in the heart called the left atrial appendage. People with atrial fibrillation who are at high risk for stroke and bleeding may be able to stop blood thinners after the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have atrial fibrillation (not caused by heart valve problems) and a CHA2DS2-VASc score of 2 or higher (a measure of stroke risk)
- You have at least one high risk for bleeding according to the Munich consensus document
- You have had a special heart imaging test (TEE or CCTA) to make sure there is no blood clot in the left atrial appendage and that your anatomy is suitable for the device
- You are willing to provide written informed consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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