Closing a heart pocket to prevent strokes in atrial fibrillation
Part of Heart & circulation clinical trials.
This study compares two similar devices that close off a small pocket in the heart to reduce stroke risk in people with atrial fibrillation who cannot take blood thinners safely. The goal is to see which device works better and is safer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You have atrial fibrillation (irregular heartbeat) not caused by a heart valve problem.
- You have a higher chance of stroke (score of 2 or more) and a high risk of bleeding.
- You need a heart ultrasound or CT scan before the procedure to check the heart's shape.
- You cannot need blood thinners for any reason other than atrial fibrillation.
- You must be willing to join and follow the study requirements.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
This study compares two devices (LAmbre and AMPLATZER Amulet) that are placed in the heart to prevent strokes in people with atrial fibrillation who cannot take blood thinners. If you join, you will be randomly assigned to get one of the two devices.
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
This trial tests a device that closes off a small pouch in the heart where blood clots can form in people with atrial fibrillation. This may help reduce the risk of stroke without needing long-term blood thinners.
This trial tests the Zenith system, a device that seals off a heart area called the left atrial appendage to reduce stroke risk in people with atrial fibrillation (AF). You may be eligible if you have AF and a doctor recommends LAA closure, and you can return for follow-up scans and visits.
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