Closing a heart pouch to prevent stroke in atrial fibrillation
Part of Heart & circulation clinical trials.
This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have atrial fibrillation (an irregular heartbeat) that is not caused by a heart valve problem and is not a one-time event.
- Your risk of stroke must be moderate to high, as determined by a standard score.
- You must be able to take blood thinners and antiplatelet drugs (to prevent clots) as required by the study.
- You must not have had a stroke, mini-stroke, or heart attack within the last 3 months.
- You must not have severe heart failure (class IV) or prior open-heart surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
This trial tests a procedure to close off a small pouch in the heart called the left atrial appendage, which is a common source of blood clots in people with atrial fibrillation. The goal is to lower your stroke risk without needing to take blood thinners long-term.
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
This study compares a procedure to close a small pouch in the heart (which is a common source of blood clots causing stroke) to using medications alone in people with atrial fibrillation who cannot safely take blood thinners. The goal is to see if this procedure can reduce stroke risk without the bleeding risks of long-term blood thinners.
This study tests a procedure called left atrial appendage occlusion. It blocks off a small pouch in the heart where blood clots can form, to reduce stroke risk without needing long-term blood thinners. This might help kidney dialysis patients who have atrial fibrillation, even though they are on dialysis.
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