Study of neuromyelitis optica spectrum disorders
Part of Brain & nervous system, Immune system & allergy clinical trials.
This study follows people with NMOSD (a rare autoimmune disease that can cause vision loss and paralysis) to learn more about the condition. It may help doctors better understand and treat NMOSD in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with NMOSD (neuromyelitis optica spectrum disorders) according to current guidelines
- You tested positive for AQP4 antibodies in your blood
- You are willing and able to give permission to join the study
- You do not have other serious illnesses (like cancer), severe mental health conditions, or a recent nervous system infection
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares several medications to see which works best for NMOSD, an autoimmune disease that can cause vision loss and paralysis. You must have a specific antibody (AQP4-IgG) to join.
This trial tests an antibody treatment for people having a neuromyelitis optica (NMO) relapse. It may reduce nerve damage from inflammation during an acute attack.
This study tests if ravulizumab can lower certain nerve damage markers in people with AQP4-positive neuromyelitis optica. It may help understand how well the treatment works.
This is a registry that collects health information from adults with neuromyelitis optica spectrum disorder (NMOSD). It aims to better understand NMOSD and support future research, including studies of emerging therapies.
This study looks at patients with neuromyelitis optica spectrum disorder (NMOSD)—a rare condition affecting the nervous system—who are doing well on rituximab treatment. Researchers want to understand hidden signs of disease activity that might predict future problems, even when patients feel stable.
This trial tests a new drug called IMC-002 for people with neuromyelitis optica spectrum disorder (NMOSD) who have a specific antibody (AQP4+). It aims to see if IMC-002 is safe and effective at preventing attacks.
Hear when a new NMOSD trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.