Clin2
NCT07267624Possibly a fitNot yet recruiting

Early antibiotic adjustment for severe pneumonia

VAP - Ventilator Associated PneumoniaAntibioticAntibiotic StewardshipAntibiotic Prescribing for Acute Respiratory-tract InfectionsIntensive Care (ICU)

Part of Infections, Lungs & breathing clinical trials.

This study tests whether adjusting antibiotics early, based on test results, can improve treatment for patients with severe pneumonia who are on a breathing machine in the intensive care unit. It aims to make antibiotic use more effective and reduce side effects.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
170 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You are in the intensive care unit and have been on a breathing machine (ventilator) for at least 48 hours.
  • You are currently receiving antibiotics for a suspected lung infection (pneumonia) that started while on the ventilator.
  • Your doctors expect you to live for at least 4 more days (96 hours).
  • You have not taken part in this trial before and are not in another study that changes how your antibiotics are given.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07202234Not yet recruiting
Phage therapy for ventilator-associated pneumonia from drug-resistant bacteria

This trial tests a treatment that uses special viruses (called phages) to kill antibiotic-resistant bacteria causing pneumonia in people on ventilators. If you're eligible, this new approach might help fight the infection when standard antibiotics aren't working well.

NCT05124977Recruiting
Antibiotic plan study for ventilator pneumonia in ICU

This trial tests an “antibiotic stewardship” approach—choosing and adjusting antibiotics in a smarter way—for a first episode of pneumonia in patients on a breathing machine. It may help ensure the right antibiotics are used at the right time, while avoiding unnecessary or overly broad treatment.

Clichy-sous-Bois
NCT07403474Recruiting· Phase 4
Using rapid testing to guide antibiotic choice in ventilator pneumonia

This trial tests whether using a rapid test to find the exact bacteria causing your pneumonia can help doctors choose the right antibiotics faster, which might improve your recovery. The study compares this approach to usual care in patients on ventilators.

Alès
NCT06743529Recruiting
Antibiotics right away or later for lung infections from a breathing machine

This study looks at when to start antibiotics for a lung infection you may have gotten while on a breathing machine. It compares starting them right away versus waiting for the test results to be sure you need them.

Angers, France
NCT05405491Recruiting
DNA test to guide antibiotic use for pneumonia in ICU patients

This study tests whether using a DNA test on lung fluid can help doctors choose better antibiotics for pneumonia in ICU patients with weakened immune systems. It may lead to more effective treatment and fewer side effects.

Lille
NCT07326540Recruiting· Phase 3
Testing a new antibiotic for drug-resistant pneumonia in the hospital

This trial compares a new antibiotic (BV100 plus low-dose polymyxin B) against a standard treatment for pneumonia caused by a hard-to-treat bacteria (Acinetobacter baumannii). If you have hospital-acquired or ventilator-associated pneumonia and standard antibiotics aren't working, this study may offer a new option.

Tbilisi

Hear when a new Antibiotic Stewardship trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.