Study of CK-4021586 for heart failure with preserved ejection fraction
Part of Heart & circulation clinical trials.
This trial tests an investigational drug called CK-4021586 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug is safe and well-tolerated. You may qualify if you are 40 to 85, have heart failure symptoms, and have a heart that pumps well but shows signs of strain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 85 years old.
- You have heart failure with symptoms during mild activity (NYHA class II or III).
- Your heart's pumping strength (LVEF) is 60% or higher.
- Your blood test shows a high level of NT-proBNP (a marker of heart strain).
- Your body mass index (BMI) is under 40.
- You are on stable doses of certain heart medications for at least 30 days, and if you take a GLP-1 drug (like Ozempic), it must be stable for at least 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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