Study of a new drug for heart failure with pulmonary hypertension
Part of Heart & circulation, Lungs & breathing clinical trials.
This study tests an investigational drug (HS235) for people who have both heart failure with preserved ejection fraction and a type of pulmonary hypertension that can happen with it. The goal is to see if the drug can improve symptoms and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old.
- You have a specific type of heart failure called HFpEF (heart failure with preserved ejection fraction).
- You have been diagnosed with pulmonary hypertension (high blood pressure in the lungs) confirmed by a heart catheterization procedure.
- Your body mass index (BMI) is between 25 and 50, and you weigh no more than 140 kg (about 308 lbs).
- You have some heart failure symptoms but are able to walk at least 100 meters (about the length of a football field) on your own.
- You have been on a stable dose of water pills (diuretics) for at least a few weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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