Study of HS235 in obese patients with pulmonary hypertension and heart failure
Part of Heart & circulation, Lungs & breathing clinical trials.
This trial tests an investigational drug called HS235 in people who have both obesity (BMI 30-50) and a specific type of heart failure with preserved pumping function, along with high blood pressure in the lungs. The goal is to see if the drug can improve symptoms and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have established heart failure with preserved ejection fraction (a type of heart failure where the heart pumps normally but is too stiff to fill properly).
- You have pulmonary hypertension (high blood pressure in the lungs) confirmed by a test.
- You are in NYHA class II or III, meaning heart failure symptoms with ordinary activity or less.
- Your body mass index (BMI) is between 30 and 50.
- You can walk at least 100 meters in 6 minutes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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