Pacing and heart pressure in HFpEF exercise
Part of Heart & circulation clinical trials.
This study tests whether a special pacing setting during exercise can help improve heart filling pressures in people with heart failure with preserved ejection fraction (HFpEF) who already have a DDD pacemaker. If you have HFpEF and a pacemaker, you may help researchers find better ways to manage your condition during activity.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and have signed a consent form.
- You have heart failure with preserved ejection fraction (your heart pumps at least 45% normally but doesn't relax properly).
- You have a DDD pacemaker with left bundle branch area pacing that was put in at least 12 weeks before the study.
- You are on optimal heart failure medications (MRA and SGLT2i) or can't take them due to side effects.
- You have normal sinus rhythm (not atrial fibrillation) during the study tests.
- You do not have severe lung disease, severe heart valve disease, or other major heart issues like unstable arrhythmias or amyloid cardiomyopathy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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