Paced heart rate increase for heart conditioning
Part of Heart & circulation clinical trials.
This trial tests whether a special pacing pattern can strengthen your heart's pumping ability. You may qualify if you have heart failure with a low ejection fraction and already have a pacemaker or defibrillator with an atrial lead.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have heart failure with a reduced pumping strength (ejection fraction of 40% or less) despite taking heart medications for at least 3 months.
- You have mild to moderate heart failure symptoms (such as shortness of breath or fatigue during everyday activities).
- You have a pacemaker or defibrillator that includes a wire in the upper chamber of your heart, and it has been in place for more than 3 months.
- Your heart's natural electrical signal is 120 milliseconds or less, or if you have a biventricular pacemaker, the paced signal is 120 milliseconds or less.
- You are 18 or older, can walk safely, and have transportation to study visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new way to pace the heart in people with heart failure who need a pacemaker. It aims to see if this pacing method helps them exercise more easily.
This study tests a new way to pace the heart to see if it can improve how well the heart pumps. It uses a special Abbott pacemaker to pace a part of the heart called the left bundle branch and adjust the timing to match your natural heart rhythm.
This study tests a new pacing approach for people with a specific type of heart failure (HFpEF) to see if it can improve symptoms and quality of life. It involves a pacemaker-like device that adjusts heart rate based on your needs.
This trial tests two pacing approaches to see which one better prevents weakening of the heart's main pumping chamber. It's for people who need a pacemaker for a slow heart rhythm and are expected to rely on it heavily.
This study looks at whether a high-intensity “His bundle” heart pacing method can help people with heart failure who have a specific heart rhythm pattern on ECG. It likely aims to improve heart pumping and symptoms in people who are otherwise a good match for an ICD and meet other criteria.
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
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