Ablation vs. standard care for older adults with AFib
Part of Heart & circulation clinical trials.
This trial compares a procedure called catheter ablation (which uses heat to destroy tiny areas of heart tissue causing irregular rhythms) with usual medical care in adults aged 78 and older who have atrial fibrillation (AFib). The goal is to see if the ablation improves outcomes and quality of life compared to standard medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 78 years of age or older.
- You have been diagnosed with atrial fibrillation (AFib) by an ECG.
- Your AFib may come and go (paroxysmal), be constant (persistent), or have been constant for a long time (longstanding persistent).
- Your doctor believes you are a good candidate for the ablation procedure based on heart guidelines.
- You have a low to moderate burden of other health conditions (measured by a score of 7 or less on a standard health index).
- Your left atrium (upper heart chamber) is not severely enlarged (less than 55 mm on an ultrasound in the past year).
- You have not had a heart attack or heart bypass surgery in the last 12 weeks.
- You do not have severe heart valve disease or congenital heart disease.
- You have not had a prior ablation or AV-node ablation for AFib.
- You are able and willing to take blood thinners (anticoagulants).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study investigates whether a catheter ablation procedure can improve wellbeing and reduce the risk of serious events for people 80 and older with symptomatic atrial fibrillation. The goal is to see if this treatment offers better outcomes than standard care in this age group.
This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.
This trial tests two different ablation techniques to treat a type of irregular heartbeat that doesn't go away on its own. It aims to find which approach works better and is safer.
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
This trial compares two catheter ablation techniques for people with persistent atrial fibrillation (a type of irregular heartbeat that doesn't go away on its own). It will test whether a more extensive ablation (burning more heart tissue) works better than the standard procedure of isolating the pulmonary veins (the veins that bring blood from the lungs to the heart). If you have this condition and have had at least one episode in the past year, this study might help you find a more effective treatment.
This study compares two treatments for atrial fibrillation (a type of irregular heartbeat) in older adults: one targets the source of the irregular rhythm (pulmonary vein isolation) and the other slows the heart rate by disabling the natural pacemaker area and placing a permanent pacemaker (AV node ablation). It helps patients decide which approach may work best for them.
Hear when a new Atrial Fibrillation Ablation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.