N-acetylcysteine for severe infections
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial tests if N-acetylcysteine, a medicine that helps the liver and fights inflammation, can improve outcomes for adults with a severe infection and liver stress.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a suspected infection confirmed by a doctor.
- Your liver function must be impaired, as measured by a MELD score of 9 or higher.
- You cannot have been in the hospital for more than 24 hours before starting the study.
- You must not have a known allergy to N-acetylcysteine or a history of severe allergic reactions.
- You must not have a blocked bile duct, be in severe shock, or need immediate end-of-life care.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an experimental drug called NAI for people in the intensive care unit (ICU) with severe infections like sepsis. It aims to boost your immune system to help fight the infection and improve recovery.
This trial tests a new treatment to protect and repair the layer of cells lining your blood vessels (glycocalyx) during sepsis. It aims to improve recovery from severe infections.
This study tests whether adding N-acetylcysteine to standard treatment helps people with severe alcoholic hepatitis. It may improve liver outcomes, especially for those with a high Maddrey score.
This trial tests whether the drug N-acetylcysteine (NAC) can help people with sudden liver failure that is not caused by acetaminophen (like Tylenol). If you qualify, you may receive NAC, which might help your liver recover.
This study tests whether adding N-acetylcysteine (an antioxidant supplement) to standard treatment helps fight an infection in the belly fluid of people with liver cirrhosis. It aims to improve recovery and reduce complications.
This trial tests if breathing in a medication called acetylcysteine can help prevent lung infections in patients who are on a breathing machine. If you or a loved one is on a ventilator, this treatment might reduce the chance of getting ventilator-associated pneumonia.
Hear when a new Sepsis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.