Siegel Valve for Severe Aortic Stenosis (TAVR)
Part of Heart & circulation clinical trials.
This study tests a new replacement valve called the Siegel, placed through a catheter in your leg (TAVR), for people with severe aortic stenosis. It aims to see if it is safe and effective for patients at low, intermediate, or high surgical risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe narrowing of your aortic valve (a heart valve) that causes symptoms
- A heart team (surgeon and cardiologist) has decided a catheter-based valve replacement (TAVR) is right for you
- Your leg arteries are large enough for the delivery system
- You do not have severe kidney disease requiring dialysis
- You have not had a heart attack in the last month
- You are at least 18 years old and can attend follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how safe and effective the SAPIEN 3 valve is for patients in China who have a specific type of bicuspid aortic valve (Type-0) that is severely narrowed. If you have severe aortic stenosis and meet the criteria, this treatment might be an option for you.
This study compares regular monitoring (“clinical surveillance”) versus replacing the aortic valve using a minimally invasive procedure called TAVR for people with moderate aortic stenosis. It aims to see which approach better reduces symptoms or heart damage over time.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
This study looks at how safe and effective an emergency heart valve replacement is for people with severe aortic stenosis who are in critical condition. It may help if you have severe symptoms like shock or unstable chest pain that need urgent treatment.
This study tests a new computer software that helps doctors place a replacement heart valve more precisely. It's for people with severe aortic stenosis who need a transcatheter aortic valve replacement (TAVR).
Hear when a new Aortic Stenosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.