Siegel Valve for Severe Aortic Stenosis (TAVR)
Part of Heart & circulation clinical trials.
This study tests a new replacement valve called the Siegel, placed through a catheter in your leg (TAVR), for people with severe aortic stenosis. It aims to see if it is safe and effective for patients at low, intermediate, or high surgical risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe narrowing of your aortic valve (a heart valve) that causes symptoms
- A heart team (surgeon and cardiologist) has decided a catheter-based valve replacement (TAVR) is right for you
- Your leg arteries are large enough for the delivery system
- You do not have severe kidney disease requiring dialysis
- You have not had a heart attack in the last month
- You are at least 18 years old and can attend follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares a less invasive valve replacement (TAVR) with traditional open-heart surgery for people with a specific type of severe aortic valve narrowing (bicuspid valve). It aims to see which approach works better for those at intermediate or low surgical risk.
This study compares regular monitoring (“clinical surveillance”) versus replacing the aortic valve using a minimally invasive procedure called TAVR for people with moderate aortic stenosis. It aims to see which approach better reduces symptoms or heart damage over time.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
This study tests a new replacement valve for the aortic heart valve, delivered through a catheter (a thin tube) — a procedure called TAVR. It is for people who have severe aortic stenosis and are not good candidates for open-heart surgery.
This study looks at how safe and effective emergency aortic valve replacement is for people with severe aortic stenosis, a condition where the heart's main valve becomes narrow. It aims to help patients who are in critical condition, such as those in shock or with dangerous heart rhythms, by replacing the valve urgently.
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