Clin2
NCT07287930Possibly a fitNot yet recruiting

YTS109 Cell Therapy for Hard-to-Treat Autoimmune Hemolytic Anemia

Autoimmune Hemolytic Anemia

Treatments studied

Part of Blood & lymphatic, Immune system & allergy clinical trials.

This trial tests a new cell therapy called YTS109 for people with autoimmune hemolytic anemia (AIHA) that hasn't improved with standard treatments. The goal is to see if this therapy can help control the disease when other options have failed.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
13 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with autoimmune hemolytic anemia or Evans syndrome, and your symptoms (like low hemoglobin) have not improved after at least three previous treatments.
  • Your organs are working well enough, including your liver, kidneys, lungs, and bone marrow.
  • You can manage your daily activities with little or no help (ECOG score of 2 or less).
  • You agree to use birth control if you could become pregnant or get someone pregnant, starting from enrollment until 12 months after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07453836Not yet recruiting· Phase 1
YTS109 cell therapy for hard-to-treat autoimmune hemolytic anemia

This trial tests an experimental cell therapy called YTS109 for people with autoimmune hemolytic anemia (AIHA) that hasn't improved after at least three prior treatments. It aims to see if the therapy can help control the disease and improve anemia symptoms.

Beijing
NCT06770504Not yet recruiting· Phase 1
YTS109 cell therapy for hard-to-treat autoimmune hemolytic anemia

This trial tests a new cell therapy (YTS109) for people with autoimmune hemolytic anemia (AIHA) that has not responded to at least three prior treatments. The goal is to see if this therapy can help control the disease.

NCT07585071Not yet recruiting· Phase 1
IASO206 cell therapy for hard-to-treat autoimmune hemolytic anemia

This trial tests a new type of cell therapy (IASO206) for patients whose autoimmune hemolytic anemia (a condition where the body attacks its own red blood cells) has not responded to standard treatments. The therapy is designed to target and control the immune cells causing the problem.

NCT06733610Recruiting· Phase 1
CAR T-cell therapy for AIHA after 3 failed treatments

This trial tests a new type of immunotherapy called CAR T-cell therapy that targets two markers on your immune cells (CD19 and BCMA). It is for people with autoimmune hemolytic anemia (AIHA) who have already tried at least 3 standard treatments without success.

Tianjin, Tianjin Municipality
NCT07748533Recruiting· Phase 1
CAR T-cell therapy for hard-to-treat autoimmune hemolytic anemia

This trial tests a new treatment using your own immune cells (CAR T-cells) to stop them from attacking your red blood cells. It is for people with autoimmune hemolytic anemia or Evans syndrome who have not improved after at least 3 previous treatments.

Tianjin
NCT06920446Not yet recruiting· Early Phase 1
Modified immune cell therapy for hard-to-treat autoimmune hemolytic anemia

This trial tests a new treatment using a patient's own immune cells that are modified to find and attack specific targets (CD19 and BCMA) on faulty B cells. It is designed for adults with autoimmune hemolytic anemia (AIHA) that has not improved after at least 3 standard treatments.

Hear when a new Autoimmune Hemolytic Anemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.