YTS109 cell therapy for autoimmune hemolytic anemia
Treatments studied
Part of Blood & lymphatic, Immune system & allergy clinical trials.
This study tests an experimental cell therapy called YTS109 for people with autoimmune hemolytic anemia (AIHA) or Evans syndrome that has not improved with standard treatments. The goal is to see if this therapy can help control the anemia and reduce the need for ongoing treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 60 years old.
- You need a confirmed diagnosis of autoimmune hemolytic anemia (AIHA) or Evans syndrome, including types like warm antibody, mixed, or cold agglutinin disease.
- You have tried at least three standard treatments (like steroids, rituximab, or other immune-suppressing drugs) and your anemia (low red blood cell count) still persists or comes back.
- Your vital organs (liver, kidneys, lungs) need to be functioning well enough, and your oxygen level should be at least 92%.
- You must be generally able to care for yourself (ECOG score of 2 or less).
- If you can become pregnant or father a child, you must agree to use contraception during the study and for 12 months after.
- You cannot have certain other serious conditions, such as recent blood clots, active infections, or previous organ or stem cell transplants.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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