Comparing blood-clotting medicines for trauma patients needing many transfusions
Part of Blood & lymphatic, Heart & circulation, Injuries & trauma clinical trials.
This trial looks at two medicines (PCC and recombinant activated Factor VIIa) that help blood clot, to see which works better for trauma patients who need a lot of blood transfusions. If you have a severe injury and need many blood transfusions quickly, this study may help identify the best treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a severe injury from a trauma (like a car crash or fall) that was serious enough to activate the highest trauma response.
- You must need a massive transfusion, meaning at least 3 units of blood within the first hour or 10 units within the first day.
- You cannot have a traumatic heart injury.
- You cannot be on blood-thinning medicine before the injury.
- You cannot be pregnant or have a terminal illness before the injury.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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