Clin2
NCT07305623Worth exploringNot yet recruiting

Stem cell repair for cleft gum in children

Cleft Lip Palate

Part of Genetic & congenital, Mouth & dental clinical trials.

This trial tests a new way to repair a cleft in the gum area using the child's own stem cells from baby teeth. It aims to help the bone heal better and avoid a second surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
205 people
Ages
7 years to 12 years
Study type
Interventional

Who can take part

  • Child is between 7 and 12 years old at the time of surgery.
  • Has a cleft lip and palate on one side (unilateral) that goes through the gum area.
  • Has not had any previous surgery for the gum cleft.
  • Baby teeth with stem cells are already stored in a biobank.
  • The permanent canine tooth has not yet erupted.
  • Child is generally healthy and up-to-date on vaccinations.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06795919Not yet recruiting
Bone graft with or without membrane for cleft gum repair

This trial compares two ways to repair a gap in the gum ridge (where teeth come through) in children with a cleft. One method uses bone from the hip with a special membrane, and the other uses bone alone. The goal is to find out which approach gives better healing and supports healthy teeth.

Cairo, Giza Governorate
NCT06585566Recruiting
Bone graft trial for children with cleft palate

This trial tests a new way to repair a gap in the upper jawbone (called an alveolar cleft) using thin layers of bone, called cortical shells, taken from the patient's own body. It is for children who have not had this surgery before and who are generally healthy.

Cairo
NCT06408337Recruiting· Phase 1/Phase 2
Biocleft for cleft palate repair in children

This trial tests a new treatment called BIOCLEFT, made from your child's own cheek cells, to help repair a complete cleft palate on one side. It aims to see if the treatment is safe and works better than standard surgery.

Granada, Spain/Granada
NCT07612423Not yet recruiting
Bone graft options for adults with cleft palate

This study compares two ways to rebuild the gap in the upper gum (alveolar cleft) using bone taken from either the jaw or the hip. It aims to see which method works better for people who missed the earlier treatment window.

NCT07442279Not yet recruiting
Hip bone graft types for bilateral cleft repair

This trial compares two ways to rebuild the upper gum area in children with a cleft on both sides. One method uses a single solid piece of bone from the hip, the other uses smaller bone chips. The goal is to find which works better for a strong, healthy result.

Cairo, Cairo Government
NCT07867067Not yet recruiting· Phase 2
Gum stem cell therapy for deep bone defects

This trial tests a new treatment for deep gum pockets caused by bone loss around teeth. The treatment uses tiny particles from gum stem cells to help the bone and gums heal after initial gum therapy.

Cairo

Hear when a new Cleft Lip Palate trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.