Isolating pulmonary veins during open-heart surgery for atrial fibrillation
Part of Heart & circulation clinical trials.
This study tests a technique to isolate the pulmonary veins (the vessels that bring blood from the lungs to the heart) in people having open-heart surgery. It aims to treat atrial fibrillation (irregular heartbeat) at the same time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having heart surgery that involves a cut through the breastbone (sternotomy).
- During the surgery, the doctor will use a device to create a 'box' around the veins that bring blood from your lungs to your heart (pulmonary veins) to treat atrial fibrillation (irregular heartbeat).
- You are an adult (18 years or older).
- You have atrial fibrillation (paroxysmal, persistent, or permanent) that has lasted less than 5 years.
- Your left atrium (upper left heart chamber) is not severely enlarged (volume less than 60 ml/m²).
- You are not pregnant or breastfeeding, and you are able to take long-term blood thinners.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new way to measure electrical signals in the heart during a procedure called pulmonary vein isolation, which is used to treat atrial fibrillation (an irregular heartbeat). It aims to improve the accuracy of the treatment, which may help your heart stay in a normal rhythm for longer.
This trial compares different techniques for a second heart ablation procedure in people with atrial fibrillation (AFib) who have already had one ablation. It aims to find the best approach to stop AFib from coming back.
This study compares two extra ablation procedures done along with standard pulmonary vein isolation in people with persistent atrial fibrillation. Both aim to stop abnormal electrical signals that drive atrial fibrillation, and the study will see which approach is safer and more effective.
This study tests a new type of ablation (pulsed field ablation) for people with atrial fibrillation who haven't gotten enough relief from medication alone. It aims to see if isolating the superior vena cava along with the pulmonary veins is safe and effective.
This study compares two different treatment strategies for atrial fibrillation (an irregular heartbeat) in people who also have heart failure. One strategy uses medications only, while the other includes a procedure to restore normal heart rhythm. The goal is to find the best way to improve symptoms and outcomes.
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
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