Deep brain stimulation for severe aggression
Part of Mental health clinical trials.
This trial tests whether deep brain stimulation, a surgical treatment that uses implanted electrodes to regulate brain activity, can reduce severe and persistent aggression in adults who have not improved with other treatments. It may offer a new option for people with schizophrenia or autism who experience aggressive behavior that is hard to control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have been in isolation in a secure psychiatric unit for at least half of the time over the past 6 months.
- You have a diagnosis of schizophrenia or autism (with or without intellectual disability), and your aggression has not improved after trying standard treatments.
- You are medically stable and have no conditions that would make surgery or brain imaging unsafe.
- You are willing to use effective contraception if you are of childbearing age, and you have a negative pregnancy test.
- You are able to understand and sign a consent form, or have a legal guardian who can do so.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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