Deep brain stimulation for treatment-resistant depression
Part of Mental health clinical trials.
This trial tests a brain pacemaker (deep brain stimulation) to see if it can help people whose depression has not improved with standard medications. It aims to reduce severe depression symptoms that haven't responded to other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must have a formal diagnosis of major depression (recurrent episodes, without psychotic features).
- You must have tried at least two different antidepressant medications that didn’t work well enough.
- You must be on a stable dose of your current antidepressant for at least 4 weeks before starting.
- You must not have had prior brain stimulation treatments like ECT, TMS, or DBS for depression.
- You must not have current strong suicidal thoughts (based on a clinical scale).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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