Deep brain stimulation for treatment-resistant depression
Part of Mental health clinical trials.
This trial tests if deep brain stimulation (DBS) can help people with major depression that hasn't improved with at least two different antidepressant medications. DBS uses a surgically implanted device to send electrical pulses to specific brain areas.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with major depression (without psychosis) that comes back in episodes.
- You have tried at least two different antidepressants that didn't work well enough.
- You have been taking a stable dose of your current antidepressant(s) for at least four weeks.
- Your depression is severe, with a score of 20 or higher on a standard depression rating scale.
- You have not had certain other brain stimulation treatments (like ECT, TMS, or prior DBS) or serious conditions (like brain injury, stents, or substance abuse in the last 6 months).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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