Deep brain stimulation for treatment-resistant schizophrenia
Part of Mental health clinical trials.
This trial tests whether deep brain stimulation (DBS) — a treatment that uses a surgically implanted device to send electrical impulses to specific brain areas — can help people with schizophrenia that has not improved with standard medications. If you've tried several antipsychotics without success, this experimental treatment might offer a new option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old
- You have been diagnosed with schizophrenia for at least 5 years
- You have tried two or more antipsychotic medications (or clozapine) for at least 12 weeks each, and they didn't help or caused bad side effects
- Your current symptoms are moderate to severe (scored at least 70 on a standard schizophrenia rating scale)
- You have not changed your psychiatric medications in the last 2 months
- You do not have any implanted devices like a pacemaker or cochlear implant, and you are not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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