Sedation medication's effect on tear production during angioplasty
Treatments studied
Part of Eyes & vision clinical trials.
This study tests whether a sedative called dexmedetomidine affects how much tear your eyes make during an angioplasty procedure. It may help doctors choose the best sedation for patients who need angioplasty.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for an angioplasty (a procedure to open blocked blood vessels) with sedation but not general anesthesia.
- You can give informed consent and complete simple eye assessments.
- Your baseline tear production test (Schirmer) shows at least 1 mm, meaning you produce some tears.
- You do not have moderate or severe dry eye disease or Sjögren's syndrome.
- You have not had eye surgery in the last 3 months or have an active eye infection.
- You have not used contact lenses within 24 hours before the study starts and you are not allergic to dexmedetomidine, midazolam, fentanyl, or propofol.
- You do not have a very slow heart rate (<50 beats per minute) or certain heart block without a pacemaker.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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