Dose changes for cancer treatment in people with Duffy null
Treatments studied
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy, Skin clinical trials.
This trial tests if changing the dose of certain chemotherapy drugs can help people with a genetic trait called Duffy null avoid side effects like low white blood cell counts. It is for people with multiple myeloma or triple-negative breast cancer starting specific treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have multiple myeloma that needs treatment, or stage II or III triple-negative breast cancer
- You are about to start or are on your first cycle of either daratumumab-RVd for myeloma or carboplatin-paclitaxel-pembrolizumab for breast cancer
- You have a genetic blood trait called Duffy null, confirmed by a blood test
- You are 18 years old or older
- You are not taking any other experimental drugs for any condition
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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