Brain function study in migraine patients with heart opening
Part of Brain & nervous system clinical trials.
This study looks at how migraine with aura affects brain function in people who also have a small heart opening called a patent foramen ovale (PFO). It may help doctors understand if closing the PFO could improve migraine symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 59 years old.
- You have been diagnosed by a doctor with migraine with aura (migraine with warning signs like flashing lights).
- You have had migraines for at least 1 year, and you have at least 4 migraine days per month during a 3-month check-in period.
- You have a small opening in your heart called a patent foramen ovale (PFO), confirmed by a special ultrasound test.
- You have tried at least three different migraine prevention medications that didn't work well or caused side effects.
- You have been on a stable dose of your current migraine prevention medicine for at least 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study is for people who have migraines and a small hole in their heart called a patent foramen ovale (PFO). It will track your health over time to learn more about how these conditions are related.
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This study looks at the link between migraine with aura and a small hole in the heart called PFO. It may help researchers understand what causes migraines in some people.
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