Comparing biodegradable vs. metal heart-hole closures for migraine
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This trial compares two types of devices (biodegradable vs. metal) to close a small hole in the heart (PFO) in people who have migraine not controlled by usual treatments. It aims to see which device works better to reduce migraine attacks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with migraine (using standard criteria) for more than a year, and it severely bothers your daily life.
- You have a small hole in your heart (called a PFO) that lets blood flow the wrong way.
- You have tried at least three different migraine prevention medicines, and none of them cut your migraine attacks by half or more.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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