How gender-affirming hormones affect the immune system
Part of Hormones & metabolism clinical trials.
This study looks at how gender-affirming hormone therapy (estrogen or testosterone) affects the immune system in transgender individuals. Researchers want to understand how these hormones change immune function over time, which could help improve health care for trans people.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 50 years old.
- You have a diagnosis of gender dysphoria and are about to start gender-affirming hormone therapy (estrogen or testosterone).
- You do not have a serious immune system disease (like an immune deficiency or an autoimmune disease that requires treatment).
- You are not taking medications that suppress the immune system (like prednisolone or biologic drugs).
- You have not tested positive for HIV, hepatitis B, hepatitis C, or HTLV-1.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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