New gout pill combined with febuxostat for high uric acid
Treatments studied
Part of Bones, joints & muscles, Hormones & metabolism, Kidney & urinary clinical trials.
This trial tests an experimental tablet (SHR4640) added to the standard gout medicine febuxostat (40 mg daily) for people whose uric acid remains too high despite febuxostat alone. The goal is to see if the combination lowers uric acid more effectively and safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You must have been taking febuxostat 40 mg daily for at least 6 weeks before joining.
- Your fasting uric acid level must be at least 390 µmol/L (first test) and then at least 360 µmol/L on a repeat test while taking febuxostat.
- You must have a diagnosis of gout according to standard medical criteria.
- You must have a body mass index (BMI) between 18 and 35.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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