Gut bacteria changes after weight-loss surgery
Part of Hormones & metabolism clinical trials.
This study looks at how weight-loss surgery changes the bacteria in your gut over time, and compares it with people on a diet and with healthy-weight people. If you are having gastric bypass surgery or starting a structured diet for weight loss, this research might help understand why some people have better outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must fit one of these groups: you are planning a gastric bypass with a BMI of 35 or higher (plus health problems) or 40 or higher; you are overweight (BMI 30 or higher) and starting a structured diet; or you are a healthy-weight volunteer (BMI 18.5–24.9).
- You have not taken antibiotics in the last 3 weeks, probiotics/prebiotics in the last 4-6 weeks, or steroids in the last 8 weeks (for surgery group).
- You do not have active gut diseases like Crohn's or ulcerative colitis, ongoing gut infections, or cancer.
- You have not had major abdominal surgery, an organ transplant, or are taking immune-suppressing drugs.
- You are not pregnant or breastfeeding, and you do not misuse alcohol or drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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