Steroid Hormone Rhythms in Adrenal Nodules
Part of Hormones & metabolism clinical trials.
This study looks at how your body's natural steroid rhythms change when you have adrenal nodules. It compares people with non-secreting nodules to those with a mild hormone excess (MACS) to see if there are differences in daily cortisol patterns.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have one or more adrenal nodules (lumps on your adrenal glands) seen on a CT scan.
- You are not pregnant or breastfeeding.
- You do not have adrenal insufficiency (your adrenal glands don't make enough hormones) and are not taking steroids.
- If you take oral estrogen (like birth control pills), you have stopped for at least 6 weeks.
- You are not in another research study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing a new method (using a blood test that measures steroid hormones) to better diagnose whether adrenal nodules are causing mild hormone problems. It may help doctors decide if you need treatment or just monitoring.
This study looks at adrenal nodules found on a CT scan and checks whether your cortisol levels stay high after a medication test. It may help researchers understand what causes abnormal cortisol production and how often it happens in people with adrenal growths.
This study tests whether the drug ketoconazole can safely help regulate daily cortisol patterns in people with mild autonomous cortisol secretion (MACS), a condition where the adrenal glands make too much cortisol. It will compare how patients with MACS and healthy volunteers respond to the medication.
This study looks for a mild form of hormone overproduction (called autonomous cortisol secretion) in people who have a benign growth on their adrenal gland. You will undergo a blood test to measure how well your body suppresses cortisol after taking a single dose of dexamethasone.
This trial tests whether metyrapone or osilodrostat works better for people with MACS, a condition where the adrenal glands produce too much cortisol on their own. The goal is to help you and your doctor choose the best treatment.
This study tracks thinking and brain changes over time in people with adrenal findings that produce too much cortisol (a stress hormone) on their own. It may help doctors understand how different treatments or watchful waiting affect the brain and cognition.
Hear when a new Mild Autonomous Cortisol Secretion Adenoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.