AnchorMan Left Atrial Appendage Closure Study
Part of Heart & circulation clinical trials.
This study tests a new device (AnchorMan®) that closes a small pouch in the heart to prevent strokes in people with atrial fibrillation. It is for patients who have a high stroke risk but cannot take blood thinners long-term.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and have atrial fibrillation (a type of irregular heartbeat) that is not caused by a heart valve problem.
- You have a high risk of stroke (based on your age, health, and gender) and you either cannot take blood thinners long-term, have had bleeding problems, or have had a stroke despite taking blood thinners.
- You do not have severe heart valve disease, severe heart failure, a recent heart attack (within 3 months), or a blood clot in your heart.
- You have not had a new stroke or mini-stroke in the last 30 days, and you are not allergic to aspirin, clopidogrel, heparin, or contrast dye.
- Your kidney function is good enough (not on dialysis and eGFR above 45), and you can take blood thinners for at least 2 months after the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
This trial compares two different devices (Amplatzer Amulet and LAmbre) used to close a small pouch in the heart called the left atrial appendage. People with atrial fibrillation who are at high risk for stroke and bleeding may be able to stop blood thinners after the procedure.
This trial tests if closing the left atrial appendage with a special stitch during planned heart surgery can help prevent strokes in people with atrial fibrillation. If you already need heart surgery, this extra step may reduce your future stroke risk.
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
This study compares two devices (LAmbre and AMPLATZER Amulet) that are placed in the heart to prevent strokes in people with atrial fibrillation who cannot take blood thinners. If you join, you will be randomly assigned to get one of the two devices.
This trial compares a simpler procedure to the standard one for closing the left atrial appendage in people with non-valvular atrial fibrillation. The goal is to see which approach works better for preventing strokes while lowering bleeding risks.
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