Ibuprofen during lung surgery for brain protection
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether giving an anti-inflammatory painkiller called ibuprofen through an IV during lung surgery helps keep the brain well-oxygenated and protects thinking and memory after the operation. If you are having a VATS lobectomy or segmentectomy, this could help preserve your mental sharpness after recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You need to be having a lobectomy or segmentectomy (removing part of a lung) using VATS, which is a minimally invasive surgery with one lung deflated.
- Your overall health should be good, as classified by doctors as ASA I-III (with no severe heart or lung problems).
- You must not have taken nonsteroidal anti-inflammatory drugs (NSAIDs like ibuprofen or naproxen) in the last 30 days, and you must not be allergic to them.
- You must not have severe chronic lung disease, kidney problems, liver disease, or a history of head injury or stroke.
- You must be able to complete a simple memory and thinking test before surgery (scoring above 24 points).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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