Clin2
NCT07408856Possibly a fitNot yet recruiting

A trial of CAN1012 for early breast changes (DCIS and LCIS)

Ductal Carcinoma in SituLobular Carcinoma in Situ

Part of Cancer, Skin clinical trials.

This trial tests a new drug called CAN1012 in people with pre-cancerous breast conditions called DCIS or LCIS. It aims to see if the drug can help before invasive cancer develops.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
24 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have DCIS or LCIS confirmed by a biopsy, with a single spot between 1 cm and 5 cm on imaging.
  • You must be 18 years or older.
  • You must be in generally good health, able to do daily activities with little or no help.
  • You must have adequate blood counts and kidney/liver function.
  • You must agree to use non-hormonal birth control during the study and for 165 days after the last dose.
  • You cannot have certain medical conditions or take specific medications, like high-dose steroids or hormonal birth control.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06218303Recruiting· Phase 1
Vaccine for early breast cancer (DCIS)

This trial tests a vaccine that targets a protein (MUC1) found in early breast cancer cells. It's for women with ER+ DCIS who are planning surgery, to see if the vaccine can help prevent the cancer from coming back or getting worse.

Pittsburgh, Pennsylvania
NCT07620496Not yet recruiting· Phase 1
CAN1012 Treatment for Pre-cancerous Mouth Tissue Changes

This study tests a new drug called CAN1012 to treat oral epithelial dysplasia, which are pre-cancerous changes in the mouth lining. The goal is to see if this drug can help prevent these changes from becoming cancer.

NCT04797299Recruiting
Testing surgery alone for low-risk ductal carcinoma in situ

This trial studies whether removing the abnormal breast cells with breast-conserving surgery only (without additional treatment) is enough for people with low-risk ductal carcinoma in situ (DCIS). It may help some patients avoid extra treatments if their risk is very low.

Calgary, Alberta
NCT07664150Recruiting· Phase 1/Phase 2
Testing a new drug for HER2-positive cancers after other treatments stop working

This trial tests a new drug, CAN016, for people with advanced solid tumors that have HER2 expression or a HER2 gene change. You may qualify if your cancer has gotten worse after trying other HER2-targeted treatments.

Beijing, Beijing Municipality
NCT05504707Recruiting· Phase 1
Study drug for early-stage, HER2-negative, low-risk hormone breast cancer

This Phase 1 trial tests a new study drug called DC1 given before standard breast cancer treatments. It focuses on people with HER2-negative breast cancer that is “hormone negative” or “hormone low,” aiming to see if the treatment is safe and whether it may work before surgery or other local therapy.

Tampa, Florida
NCT07245316Not yet recruiting
Avoiding surgery for early breast changes with hormone therapy

This trial tests whether taking endocrine therapy (medication that blocks estrogen) can help some women with very early breast changes (like DCIS or ADH) avoid surgery. It is for women whose cells are strongly estrogen receptor positive and not HER2 positive.

Seoul

Hear when a new Ductal Carcinoma in Situ trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.