Mitral valve replacement using a catheter for severe leaky valve
Part of Heart & circulation clinical trials.
This trial tests a new way to replace the mitral valve using a soft tube (catheter) inserted through the leg, for people with severe leaky mitral valve who are not candidates for traditional surgery or clip repair. It aims to see how well this valve works in real-world patients across Europe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older and have severe or moderately severe mitral regurgitation (a leaky mitral valve).
- Your heart's pumping strength (called ejection fraction) must be at least 30%.
- Your heart's main pumping chamber size must be 70 mm or less (measured by your doctor).
- Your heart team must decide that traditional heart surgery is not a good option for you.
- Your heart team must also decide that a less invasive clip repair (called TEER) is not suitable for you.
- You must not have severe calcium build-up or hardened mitral valve tissue, or narrow leg arteries that block the catheter pathway.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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