Registry for catheter-based mitral valve replacement
Part of Heart & circulation clinical trials.
This registry is testing a new, less invasive way to replace your mitral valve using a catheter. It's for people who cannot have open-heart surgery or a MitraClip, and who have a strong enough heart.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe or moderately severe mitral valve leakage that is not suitable for open-heart surgery or a MitraClip.
- Your heart's pumping strength is at least 30% (LVEF ≥ 30%).
- Your left ventricle is not too large (LVEDD ≤ 70 mm).
- You are at least 18 years old.
- You do not have severe calcium deposits in your mitral valve or narrow leg arteries that would block the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a new catheter-based valve replacement system for people with moderate to severe, or severe, mitral valve regurgitation (a leaky mitral valve). It aims to check whether the procedure is safe and can improve heart function compared with expected care.
This trial studies a newer, catheter-based mitral valve treatment in people with moderate-severe to severe mitral valve leaking who are at high risk for open-heart surgery. It may help improve symptoms and heart function without traditional surgery, but you must meet key heart, anatomy, and safety requirements.
This trial studies a catheter-based procedure to replace the mitral valve in people with severe (or specific moderate) mitral valve leakage that causes symptoms. It may help by reducing leaking and related symptoms when standard surgery or less invasive fixes aren’t suitable for you.
This study tests a new device that replaces a leaking mitral valve without open-heart surgery. It may help people who have severe mitral valve leakage but cannot safely have standard surgery or some other less invasive valve repairs.
This study looks at how safe and effective a specific catheter procedure is for people with moderate-to-severe mitral valve leakage. It may help those who are considered high risk for traditional open-heart surgery.
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
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