Spironolactone for HIV-infected adults
Treatments studied
Part of Injuries & trauma clinical trials.
This study tests the drug spironolactone, a medicine that helps your body balance fluids and potassium, in both HIV-positive and HIV-negative adults. The goal is to see how it affects a key protein complex in your cells. If you are HIV-positive, you need to have well-controlled HIV with undetectable virus levels and be on stable treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You can give written permission to be in the study.
- If you have HIV, you must have a confirmed HIV diagnosis, be on a stable antiretroviral therapy, and have an undetectable HIV viral load.
- If you do not have HIV, you must have a negative HIV test at screening.
- You must not be pregnant, breastfeeding, or plan to become pregnant during the study.
- You must not be allergic to spironolactone or have serious kidney, liver, or heart problems.
- You must not be taking aspirin, NSAIDs (like ibuprofen), steroids, or any potassium-raising supplements/medications on a regular basis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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