Testing spironolactone with blood pressure drugs for PA
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial looks at whether adding spironolactone to your current blood pressure medicines works better for people with primary aldosteronism (a condition where your adrenal glands make too much aldosterone, raising blood pressure). You may qualify if you have this form of high blood pressure but have declined surgery or don't have an adenoma.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 65 years old
- You have primary aldosteronism (PA) confirmed by blood tests and a special saline infusion test
- You have high blood pressure (clinic reading at least 140/90, or a 24-hour monitor showing average at least 130/80)
- You have a unilateral aldosterone-producing adenoma but choose not to have surgery, or you have non-adenoma PA confirmed by adrenal vein sampling
- You are willing to sign a consent form and attend follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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