Comparing treatments for frail older adults with atrial fibrillation
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether combining a heart procedure (catheter ablation) with a device to close the left atrial appendage (LAAO) is safer or better than blood thinners alone for frail patients 75 years or older with atrial fibrillation and high stroke risk. It aims to find a treatment that reduces stroke while lowering bleeding risks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 75 years old or older.
- You have been diagnosed with atrial fibrillation (irregular heartbeat) that is not caused by a heart valve problem; it may come and go or be constant.
- Your stroke risk score (CHA2DS2-VASc) is 3 or higher.
- You can tolerate blood thinners as prescribed by your doctor.
- You are willing and able to have the procedures and follow-up visits.
- You are not severely frail (based on a frailty scale) and have a life expectancy of more than 2 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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