Ablation or pacemaker: which is right for you?
Part of Heart & circulation clinical trials.
This study compares two treatments for atrial fibrillation (a type of irregular heartbeat) in older adults: one targets the source of the irregular rhythm (pulmonary vein isolation) and the other slows the heart rate by disabling the natural pacemaker area and placing a permanent pacemaker (AV node ablation). It helps patients decide which approach may work best for them.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 65 and have persistent atrial fibrillation, or over 75 with intermittent atrial fibrillation (paroxysmal).
- You have tried at least one heart rate or rhythm medication without success, either because it didn't work or you couldn't tolerate it.
- An ECG performed while sitting quietly shows your heart rate is above 70 beats per minute on medication, or above 90 without medication, while in atrial fibrillation.
- You have not had previous procedures for atrial fibrillation (like pulmonary vein isolation, left atrial flutter ablation, or AV node ablation).
- Your body mass index (BMI) is 40 or less.
- Your doctor has determined you are suitable for both pulmonary vein isolation and pacemaker implantation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two types of ablation (a procedure that uses energy to fix irregular heartbeats) for people with persistent atrial fibrillation. It tests whether adding extra treatment to the back of the heart's left upper chamber helps improve outcomes compared to standard treatment alone.
This study compares two ways to perform a heart procedure called ablation to treat atrial fibrillation, a condition that causes an irregular heartbeat. The goal is to find out which approach is safer and more effective at restoring a normal heart rhythm.
This study compares different treatments—pacing therapy, medications, and catheter ablation—for people who have both atrial fibrillation and heart failure. It aims to find the best way to improve your heart function and quality of life.
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
This trial compares a procedure called catheter ablation (which uses heat to destroy tiny areas of heart tissue causing irregular rhythms) with usual medical care in adults aged 78 and older who have atrial fibrillation (AFib). The goal is to see if the ablation improves outcomes and quality of life compared to standard medications.
This trial tests two different ablation techniques to treat a type of irregular heartbeat that doesn't go away on its own. It aims to find which approach works better and is safer.
Hear when a new Atrial Fibrillation (AF) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.