Clinical trials
Soft Tissue Infections clinical trials
Below are recruiting soft tissue infections clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT07615049RecruitingPhase 3
Shorter versus standard radiation for soft tissue sarcoma
This trial compares a shorter course of radiation therapy with the standard longer course for people with soft tissue sarcoma in an arm or leg. The goal is to see if the shorter course works just as well and may be more convenient.
Birmingham, AlabamaAges 18 years+ - NCT05899140RecruitingPhase 4
Clindamycin added to treat certain skin infections
This trial tests whether adding clindamycin helps treat skin and soft-tissue infections caused by Staphylococcus aureus. You may be eligible if your infection was diagnosed recently and a sample was collected soon after hospital admission.
MasokoriAges 18 years+ - NCT07574606Recruiting
Soft Tissue Coverage for Zygomatic Implants in Jaw Bone Loss
This study compares two surgical methods to cover zygomatic implants (special anchor posts for teeth) in patients with severe jawbone loss. Researchers will measure how much soft tissue (gum and fat) builds up over the implants to see which method produces better, longer-lasting results.
Cairo, New CairoAges 18 years+ - NCT07489274RecruitingPhase 4
Hyperbaric oxygen for severe skin infections
This trial tests whether adding hyperbaric oxygen therapy to standard care helps adults with a serious soft-tissue infection. It could improve healing and reduce complications.
Antwerp, EdegemAges 18 years+ - NCT03138161RecruitingPhase 1/Phase 2
Testing three medicines for previously treated soft-tissue sarcoma
This trial tests trabectedin plus ipilimumab and nivolumab in people with advanced soft-tissue sarcoma that has already been treated. It aims to see how well this combination works and how safely it can be given.
Santa Monica, CaliforniaAges 18 years+ - NCT07120386Recruiting
Comparing two wound vacuum methods for severe skin infections
This study compares two wound care methods after emergency surgery for a serious skin infection. One method uses a standard wound vacuum, and the other uses a wound vacuum that also irrigates (rinses) the wound to see if it helps with healing.
Saint Paul, MinnesotaAges 18 years+ - NCT07107555Enrolling by invitation
Study of severe tissue infections
This trial studies a rare but serious infection called necrotizing soft-tissue infection (NSTI), which destroys tissue quickly. It looks at how patients are treated in hospitals across Europe to improve care.
BarcelonaAges 18 years+ - NCT06968780Recruiting
Comparing two gum grafts for dental implants in the upper jaw
This trial compares two surgical techniques using tissue from the cheek or the roof of the mouth to improve gum health around special implants placed in the cheekbone. It may be an option if you have severe bone loss in your upper jaw and need implants but don't have enough bone for standard ones.
Cairo, Giza GovernorateAges 18 years+ - NCT06857708Recruiting
Wound dressings for necrotizing fasciitis wounds
This study tests two special wound dressings (Cytal® Wound Matrix and MicroMatrix®) to help heal wounds caused by a serious flesh-eating infection called necrotizing fasciitis. The goal is to see if these dressings improve healing and reduce the need for more surgeries.
Cleveland, OhioAges 18 years+ - NCT06797999RecruitingPhase 1/Phase 2
Study of ADCE-D01 for soft tissue sarcoma
This trial tests a new drug called ADCE-D01 for people with soft tissue sarcoma that has spread or cannot be removed by surgery. The goal is to see if it is safe and effective.
Aurora, ColoradoAges 18 years+ - NCT06498648RecruitingPhase 1/Phase 2
Abemaciclib with gemcitabine for soft tissue sarcoma
This trial tests whether adding the targeted drug abemaciclib to standard chemotherapy (gemcitabine) works better against certain soft tissue sarcomas. It is for people whose tumors have a normal Rb gene, which may help the drug work.
Houston, TexasAges 18 years+ - NCT06002607Recruiting
Shorter vs longer antibiotics for severe skin infections
This study compares a shorter course (about 7 days) of antibiotics to a longer course (about 14 days) for people who had surgery for a severe skin and muscle infection. The goal is to see if a shorter treatment works just as well.
Orange, CaliforniaAges 18 years+ - NCT05471908Recruiting
Compare automatic versus as-needed follow-up after common infections
This study compares two ways of scheduling a check-up after a child is hospitalized: an automatic visit or a visit only if needed (“as-needed”). It may help families and clinicians see which follow-up approach works best after illnesses like pneumonia, stomach flu (gastroenteritis), skin infections, or urinary tract infections.
Phoenix, ArizonaAges Up to 18 years - NCT05243966Recruiting
Registry for soft tissue repair using a special matrix
This study is a registry that collects information from people who had soft tissue repair using a specific matrix and/or morcell material. It may help researchers understand how this approach performs in real-world care and patient outcomes over time.
Phoenix, ArizonaAges 18 years+ - NCT04577014RecruitingPhase 1/Phase 2
Retifanlimab plus chemotherapy for advanced soft tissue sarcoma
This trial tests retifanlimab (an immunotherapy that helps your immune system recognize cancer) combined with gemcitabine and docetaxel chemotherapy. It’s for people with advanced soft tissue sarcoma that can’t be safely removed with surgery, aiming to shrink tumors and improve outcomes.
New York, New YorkAges 18 years+ - NCT03818412Recruiting
Liquid biopsy for soft tissue sarcoma
This study checks if a blood test can detect DNA from soft tissue sarcomas. The goal is to see if circulating tumor DNA can help doctors monitor the disease and plan treatment.
Toronto, OntarioAges 18 years+ - NCT03482245Recruiting
Study how body clock proteins affect immune responses in infections
This study looks at how your body’s daily “clock” proteins may influence your immune response during certain serious infections requiring hospital care. If you qualify, researchers will compare immune signals during treatment to better understand what could improve care.
St Louis, MissouriAges 18–65 - NCT06514313RecruitingPhase 2
Study of a drug combo for children with returning soft tissue sarcoma
This trial tests a combination of three drugs (VIM and VIT) for children and young adults whose soft tissue sarcoma has come back or not responded to previous treatments. The goal is to see if this new combination can help shrink or control the tumor.
Guangzhou, GuangdongAges 2–21 - NCT06506838RecruitingPhase 4
Anlotinib, chemo, and radiation before sarcoma surgery
This trial tests combining anlotinib (a targeted therapy), doxorubicin (chemotherapy), and radiation given before surgery to shrink high-grade soft tissue sarcomas. The goal is to make the tumor easier to remove and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT07602049RecruitingPhase 2
Freezing Plus Immunotherapy for Advanced Soft Tissue Sarcoma
This trial combines cryoablation (a freezing technique to destroy tumors) with camrelizumab (an immunotherapy drug that helps your immune system fight cancer) for patients with advanced soft tissue sarcoma that hasn't responded to standard treatments. The goal is to see if this combination works better than current options.
Guangzhou, GuangdongAges 14–70 - NCT07444619RecruitingPhase 1
Combination drugs for returning soft tissue sarcoma in young people
This trial tests if combining four drugs (pazopanib, trabectedin, ipilimumab, and nivolumab) can help treat soft tissue sarcomas that have come back. It is for children and young adults up to age 30.
Houston, TexasAges 1–30 - NCT07322146Enrolling by invitationPhase 4
Shorter antibiotics for children with common infections
This study tests whether shorter courses of antibiotics are as effective as longer ones for children hospitalized with pneumonia, skin infections, or urinary tract infections. It may help children get back to normal faster and reduce side effects.
Birmingham, AlabamaAges 2 months–17 years - NCT07293702Recruiting
IASTM therapy for shoulder pain from impingement
This study tests a hands-on therapy called IASTM (instrument-assisted soft tissue mobilization) to see if it can reduce pain, improve movement, and help your shoulder feel more stable. It is for people with subacromial impingement syndrome, a common cause of shoulder pain.
IstanbulAges 40–60
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Common questions
- Are there clinical trials for soft tissue infections?
- Yes. Clin2 currently lists 120 recruiting soft tissue infections studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a soft tissue infections trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a soft tissue infections trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.