Clinical trials
Soft Tissue Infections clinical trials
Below are recruiting soft tissue infections clinical trials, each written for real people, not researchers. We’re tracking 131 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06002607Recruiting
Shorter vs longer antibiotics for severe skin infections
This study compares a shorter course (about 7 days) of antibiotics to a longer course (about 14 days) for people who had surgery for a severe skin and muscle infection. The goal is to see if a shorter treatment works just as well.
Orange, CaliforniaAges 18 years+ - NCT07120386Recruiting
Comparing two wound vacuum methods for severe skin infections
This study compares two wound care methods after emergency surgery for a serious skin infection. One method uses a standard wound vacuum, and the other uses a wound vacuum that also irrigates (rinses) the wound to see if it helps with healing.
Saint Paul, MinnesotaAges 18 years+ - NCT05243966Recruiting
Registry for soft tissue repair using a special matrix
This study is a registry that collects information from people who had soft tissue repair using a specific matrix and/or morcell material. It may help researchers understand how this approach performs in real-world care and patient outcomes over time.
Phoenix, ArizonaAges 18 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT03482245Recruiting
Study how body clock proteins affect immune responses in infections
This study looks at how your body’s daily “clock” proteins may influence your immune response during certain serious infections requiring hospital care. If you qualify, researchers will compare immune signals during treatment to better understand what could improve care.
St Louis, MissouriAges 18–65 - NCT03818412Recruiting
Liquid biopsy for soft tissue sarcoma
This study checks if a blood test can detect DNA from soft tissue sarcomas. The goal is to see if circulating tumor DNA can help doctors monitor the disease and plan treatment.
Toronto, OntarioAges 18 years+ - NCT04577014RecruitingPhase 1/Phase 2
Retifanlimab plus chemotherapy for advanced soft tissue sarcoma
This trial tests retifanlimab (an immunotherapy that helps your immune system recognize cancer) combined with gemcitabine and docetaxel chemotherapy. It’s for people with advanced soft tissue sarcoma that can’t be safely removed with surgery, aiming to shrink tumors and improve outcomes.
New York, New YorkAges 18 years+ - NCT04757337RecruitingPhase 3
Oral chemotherapy comparison for older advanced soft-tissue cancer
This trial compares two chemotherapy medicines—oral cyclophosphamide versus doxorubicin—in people age 65 and older with advanced soft-tissue sarcoma that can’t be cured with surgery or radiation. It aims to see which treatment works better and is more tolerable for this age group.
ToulouseAges 65 years+ - NCT05471908Recruiting
Compare automatic versus as-needed follow-up after common infections
This study compares two ways of scheduling a check-up after a child is hospitalized: an automatic visit or a visit only if needed (“as-needed”). It may help families and clinicians see which follow-up approach works best after illnesses like pneumonia, stomach flu (gastroenteritis), skin infections, or urinary tract infections.
Phoenix, ArizonaAges Up to 18 years - NCT05899140RecruitingPhase 4
Clindamycin added to treat certain skin infections
This trial tests whether adding clindamycin helps treat skin and soft-tissue infections caused by Staphylococcus aureus. You may be eligible if your infection was diagnosed recently and a sample was collected soon after hospital admission.
MasokoriAges 18 years+ - NCT06498648RecruitingPhase 1/Phase 2
Abemaciclib with gemcitabine for soft tissue sarcoma
This trial tests whether adding the targeted drug abemaciclib to standard chemotherapy (gemcitabine) works better against certain soft tissue sarcomas. It is for people whose tumors have a normal Rb gene, which may help the drug work.
Houston, TexasAges 18 years+ - NCT06797999RecruitingPhase 1/Phase 2
Study of ADCE-D01 for soft tissue sarcoma
This trial tests a new drug called ADCE-D01 for people with soft tissue sarcoma that has spread or cannot be removed by surgery. The goal is to see if it is safe and effective.
Aurora, ColoradoAges 18 years+ - NCT06857708Recruiting
Wound dressings for necrotizing fasciitis wounds
This study tests two special wound dressings (Cytal® Wound Matrix and MicroMatrix®) to help heal wounds caused by a serious flesh-eating infection called necrotizing fasciitis. The goal is to see if these dressings improve healing and reduce the need for more surgeries.
Cleveland, OhioAges 18 years+ - NCT06968780Recruiting
Comparing two gum grafts for dental implants in the upper jaw
This trial compares two surgical techniques using tissue from the cheek or the roof of the mouth to improve gum health around special implants placed in the cheekbone. It may be an option if you have severe bone loss in your upper jaw and need implants but don't have enough bone for standard ones.
Cairo, Giza GovernorateAges 18 years+ - NCT03138161RecruitingPhase 1/Phase 2
Testing three medicines for previously treated soft-tissue sarcoma
This trial tests trabectedin plus ipilimumab and nivolumab in people with advanced soft-tissue sarcoma that has already been treated. It aims to see how well this combination works and how safely it can be given.
Santa Monica, CaliforniaAges 18 years+ - NCT07489274RecruitingPhase 4
Hyperbaric oxygen for severe skin infections
This trial tests whether adding hyperbaric oxygen therapy to standard care helps adults with a serious soft-tissue infection. It could improve healing and reduce complications.
Antwerp, EdegemAges 18 years+ - NCT07574606Recruiting
Soft Tissue Coverage for Zygomatic Implants in Jaw Bone Loss
This study compares two surgical methods to cover zygomatic implants (special anchor posts for teeth) in patients with severe jawbone loss. Researchers will measure how much soft tissue (gum and fat) builds up over the implants to see which method produces better, longer-lasting results.
Cairo, New CairoAges 18 years+ - NCT07107555Enrolling by invitation
Study of severe tissue infections
This trial studies a rare but serious infection called necrotizing soft-tissue infection (NSTI), which destroys tissue quickly. It looks at how patients are treated in hospitals across Europe to improve care.
BarcelonaAges 18 years+ - NCT07444619RecruitingPhase 1
Combination drugs for returning soft tissue sarcoma in young people
This trial tests if combining four drugs (pazopanib, trabectedin, ipilimumab, and nivolumab) can help treat soft tissue sarcomas that have come back. It is for children and young adults up to age 30.
Houston, TexasAges 1–30 - NCT04307277RecruitingPhase 3
Checking chemotherapy before and after surgery for high-risk sarcoma
This Phase 3 trial tests whether giving chemotherapy around the time of surgery (before/after) can improve outcomes for people with high-risk localized soft-tissue sarcoma. It uses special tumor testing (CINSARC) to help identify higher-risk patients who may benefit.
BesançonAges 18 years+ - NCT04776525RecruitingPhase 2
Chemotherapy before surgery for certain soft tissue sarcomas
This trial tests a step-by-step (sequential) chemotherapy plan given before surgery for adults with specific types of soft tissue sarcoma. The goal is to shrink or control the tumor before the operation and see how well this approach works and is tolerated.
BergenAges 18 years+ - NCT05679921RecruitingPhase 2
Pazopanib, with or without pembrolizumab, for metastatic soft-tissue cancer
This Phase 2 trial tests pazopanib alone or together with pembrolizumab to slow or shrink metastatic soft-tissue sarcoma after prior chemotherapy. It may help some people by strengthening the anti-cancer effect compared with pazopanib by itself.
SeoulAges 20–80 - NCT06500065Recruiting
Testing a new PET scan for soft tissue sarcoma
This study uses a special PET/CT scan (68Ga-DOTATATE) to see if it can better find soft tissue sarcomas. You will also have a standard PET/CT scan for comparison, and the results may help guide your treatment.
Columbus, OhioAges 18 years+ - NCT06506838RecruitingPhase 4
Anlotinib, chemo, and radiation before sarcoma surgery
This trial tests combining anlotinib (a targeted therapy), doxorubicin (chemotherapy), and radiation given before surgery to shrink high-grade soft tissue sarcomas. The goal is to make the tumor easier to remove and improve outcomes.
Guangzhou, GuangdongAges 18–75
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Common questions
- Are there clinical trials for soft tissue infections?
- Yes. Clin2 currently lists 131 recruiting soft tissue infections studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a soft tissue infections trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a soft tissue infections trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.